I've been designing professionally for about 3 years now, with many years before that doing freelance and commissioned work. Most of my work in the past few years has been on the computer using Photoshop, Adobe Illustrator, and Aseprite creating assets for video games. I've also used these programs in tandem with Unity and Blender 3D. I've used various other programs, but these are the ones I've spent the most time with and are proficient in.
In addition to digital work, I have a large portfolio of physical work. Before I started making art on the computer, I made art for many years with traditional materials and sometimes non-traditional. I still make tangible art very often and I never plan to stop!